| 2020 |
| 02/27 | 537 | 538 | 537 | 537 | 0% | 19,200 | 95億302万 | 0% |
| 02/26 | 538 | 539 | 537 | 537 | -0.19% | 33,400 | 95億302万 | 0% |
| 02/25 | 538 | 539 | 538 | 538 | +0.19% | 45,800 | 95億2071万 | +0.19% |
| 02/21 | 538 | 538 | 537 | 537 | 0% | 33,600 | 95億302万 | 0% |
| 02/20 | 537 | 537 | 537 | 537 | 0% | 18,800 | 95億302万 | 0% |
| 02/19 | 537 | 538 | 537 | 537 | -0.19% | 29,600 | 95億302万 | 0% |
| 02/18 | 537 | 538 | 537 | 538 | +0.19% | 64,900 | 95億2071万 | +0.19% |
| 02/17 | 537 | 538 | 537 | 537 | 0% | 73,100 | 95億302万 | 0% |
| 02/14 | （IR情報）15:00 株式併合並びに単元株式数の定めの廃止及び定款の一部変更の承認決議に関するお知らせ |
| 02/14 | 537 | 539 | 537 | 537 | 0% | 6,100 | 95億302万 | 0% |
| 02/13 | 537 | 538 | 537 | 537 | -0.19% | 4,100 | 95億302万 | 0% |
| 02/12 | 537 | 539 | 537 | 538 | +0.19% | 10,400 | 95億2071万 | +0.19% |
| 02/10 | 537 | 539 | 537 | 537 | 0% | 16,500 | 95億302万 | 0% |
| 02/07 | 538 | 539 | 537 | 537 | 0% | 17,600 | 95億302万 | +0.19% |
| 02/06 | 538 | 538 | 537 | 537 | -0.19% | 18,400 | 95億302万 | 0% |
| 02/05 | 538 | 538 | 537 | 538 | +0.19% | 4,800 | 95億2071万 | +0.19% |
| 02/04 | 538 | 538 | 537 | 537 | -0.19% | 47,400 | 95億302万 | 0% |
| 02/03 | 539 | 539 | 537 | 538 | +0.19% | 48,300 | 95億2071万 | +0.37% |
| 01/31 | （IR情報）15:00 2019年12月期決算補足説明資料 |
| 01/31 | （IR情報）15:00 2019年12月期決算短信〔日本基準〕(非連結) |
| 01/31 | 537 | 539 | 537 | 537 | 0% | 14,700 | 95億302万 | +0.19% |
| 01/30 | 538 | 539 | 537 | 537 | 0% | 29,900 | 95億302万 | +0.19% |
| 01/29 | 537 | 539 | 537 | 537 | 0% | 17,800 | 95億302万 | +0.19% |
| 01/28 | 539 | 539 | 537 | 537 | +0.19% | 18,600 | 95億302万 | +0.19% |
| 01/27 | 536 | 540 | 536 | 536 | 0% | 58,700 | 94億8532万 | 0% |
| 01/24 | 536 | 538 | 536 | 536 | 0% | 6,900 | 94億8532万 | 0% |
| 01/23 | 537 | 538 | 536 | 536 | 0% | 5,000 | 94億8532万 | 0% |
| 01/22 | 536 | 539 | 536 | 536 | 0% | 36,400 | 94億8532万 | 0% |
| 01/21 | 537 | 538 | 536 | 536 | 0% | 50,900 | 94億8532万 | 0% |
| 01/20 | 537 | 537 | 536 | 536 | -0.19% | 45,000 | 94億8532万 | 0% |
| 01/17 | 537 | 538 | 537 | 537 | 0% | 25,500 | 95億302万 | +0.19% |
| 01/16 | 537 | 538 | 537 | 537 | +0.19% | 31,800 | 95億302万 | +0.19% |
| 01/15 | 537 | 537 | 536 | 536 | 0% | 24,100 | 94億8532万 | 0% |
| 01/14 | 538 | 538 | 536 | 536 | 0% | 25,000 | 94億8532万 | 0% |
| 01/10 | 538 | 539 | 536 | 536 | -0.19% | 11,300 | 94億8532万 | -0.19% |
| 01/09 | （IR情報）15:00 株式併合並びに単元株式数の定めの廃止及び定款の一部変更に関するお知らせ |
| 01/09 | （IR情報）15:00 臨時株主総会開催日及び付議議案の決定に関するお知らせ |
| 01/09 | 537 | 539 | 536 | 537 | +0.19% | 24,500 | 95億302万 | 0% |
| 01/08 | 537 | 538 | 536 | 536 | 0% | 8,600 | 94億8532万 | -0.19% |
| 01/07 | 535 | 539 | 535 | 536 | +0.19% | 20,500 | 94億8532万 | -0.19% |
| 01/06 | 536 | 537 | 535 | 535 | 0% | 67,800 | 94億6762万 | -0.37% |
| 2019 |
| 12/30 | 539 | 539 | 535 | 535 | -0.93% | 60,800 | 94億6762万 | -0.37% |
| 12/27 | 537 | 540 | 537 | 540 | +0.56% | 45,200 | 95億5611万 | +0.56% |
| 12/26 | 536 | 538 | 536 | 537 | +0.19% | 25,700 | 95億302万 | 0% |
| 12/25 | 535 | 537 | 535 | 536 | +0.19% | 18,800 | 94億8532万 | -0.19% |
| 12/24 | 535 | 537 | 535 | 535 | 0% | 28,500 | 94億6762万 | -0.37% |
| 12/23 | 535 | 536 | 533 | 535 | 0% | 88,900 | 94億6762万 | -0.37% |
| 12/20 | （5%ルール）野村證券（0.07%）ノムラインターナショナルピーエルシー(NOMURA IN…（0.09%） |
| 12/20 | 538 | 538 | 535 | 535 | -0.56% | 14,000 | 94億6762万 | -0.37% |
| 12/19 | 535 | 539 | 535 | 538 | +0.56% | 74,300 | 95億2071万 | 0% |
| 12/18 | （5%ルール）塩野義製薬（83.62%） |
| 12/18 | 535 | 536 | 535 | 535 | 0% | 16,600 | 94億6762万 | -0.56% |
| 12/17 | 535 | 536 | 535 | 535 | 0% | 18,900 | 94億6762万 | -0.56% |
| 12/16 | 535 | 538 | 535 | 535 | +0.19% | 35,800 | 94億6762万 | -0.56% |
| 12/13 | （IR情報）15:00 臨時株主総会招集のための基準日設定に関するお知らせ |
| 12/13 | （IR情報）15:00 塩野義製薬株式会社による当社株券等に対する公開買付けの結果並びに親会社及びその他の関係会社の異動に関するお知らせ |
| 12/13 | 535 | 536 | 534 | 534 | -0.19% | 102,800 | 94億4993万 | -0.74% |
| 12/12 | 535 | 537 | 535 | 535 | -0.19% | 158,500 | 94億6762万 | -0.56% |
| 12/11 | 538 | 538 | 533 | 536 | -0.37% | 225,400 | 94億8532万 | -0.37% |
| 12/10 | 538 | 539 | 538 | 538 | -0.19% | 178,100 | 95億2071万 | 0% |
| 12/09 | 540 | 540 | 539 | 539 | 0% | 118,700 | 95億3841万 | +0.19% |
| 12/06 | 539 | 540 | 539 | 539 | 0% | 116,900 | 95億3841万 | +0.19% |
| 12/05 | 540 | 540 | 539 | 539 | 0% | 75,700 | 95億3841万 | +0.94% |
| 12/04 | 540 | 540 | 539 | 539 | -0.19% | 179,900 | 95億3841万 | +2.28% |
| 12/03 | 539 | 540 | 539 | 540 | +0.37% | 342,500 | 95億5611万 | +3.85% |
| 12/02 | 538 | 539 | 538 | 538 | 0% | 241,400 | 95億2071万 | +4.87% |
| 11/29 | 538 | 539 | 538 | 538 | 0% | 107,000 | 95億2071万 | +6.32% |
| 11/28 | 539 | 539 | 538 | 538 | 0% | 77,600 | 95億2071万 | +7.82% |
| 11/27 | 538 | 539 | 538 | 538 | -0.19% | 256,500 | 95億2071万 | +9.57% |
| 11/26 | 539 | 539 | 538 | 539 | +0.19% | 189,300 | 95億3841万 | +11.36% |
| 11/25 | 539 | 539 | 538 | 538 | 0% | 152,400 | 95億2071万 | +13.03% |
| 11/22 | 538 | 539 | 538 | 538 | 0% | 184,300 | 95億2071万 | +14.96% |
| 11/21 | （IR情報）16:30 (訂正)「塩野義製薬株式会社による当社株券等に対する公開買付けに関する意見表明のお知らせ」の一部訂正に関するお知らせ |
| 11/21 | 538 | 539 | 538 | 538 | 0% | 111,500 | 82億2951万 | +16.96% |
| 11/20 | （5%ルール）ノムラインターナショナルピーエルシー(NOMURA IN…（0.28%）野村證券（6.17%） |
| 11/20 | 539 | 539 | 538 | 538 | 0% | 191,000 | 82億2951万 | +19.03% |
| 11/19 | 538 | 539 | 538 | 538 | 0% | 137,100 | 82億2951万 | +21.17% |
| 11/18 | 538 | 539 | 538 | 538 | 0% | 264,400 | 82億2951万 | +23.39% |
| 11/15 | 538 | 539 | 538 | 538 | -0.19% | 257,300 | 82億2951万 | +25.41% |
| 11/14 | 538 | 539 | 538 | 539 | +0.19% | 279,600 | 82億4481万 | +27.73% |
| 11/13 | 538 | 539 | 538 | 538 | 0% | 302,500 | 82億2951万 | +29.64% |
| 11/12 | 539 | 539 | 538 | 538 | -0.19% | 224,100 | 82億2951万 | +31.86% |
| 11/11 | 539 | 539 | 538 | 539 | +0.19% | 301,100 | 82億4481万 | +34.75% |
| 11/08 | 538 | 539 | 538 | 538 | 0% | 302,800 | 82億2951万 | +37.24% |
| 11/07 | 538 | 539 | 538 | 538 | 0% | 510,000 | 82億2951万 | +39.74% |
| 11/06 | 538 | 539 | 538 | 538 | 0% | 1,056,000 | 82億2951万 | +42.71% |
| 11/05 | 538 | 539 | 537 | 538 | +2.09% | 3,098,700 | 82億2951万 | +46.2% |
| 11/01 | 527 | 527 | 527 | 527 | +17.9% | 266,200 | 80億6125万 | +46.39% |
| 10/31 | 447 | 447 | 447 | 447 | +21.8% | 59,300 | 68億3753万 | +27.35% |
| 10/30 | （IR情報）15:00 塩野義製薬株式会社による当社株券等に対する公開買付けに関する意見表明のお知らせ |
| 10/30 | （IR情報）15:00 2019年12月期第3四半期決算短信〔日本基準〕(非連結) |
| 10/30 | 363 | 370 | 357 | 367 | -0.27% | 99,000 | 56億1381万 | +5.76% |
| 10/29 | 361 | 372 | 358 | 368 | +1.94% | 110,800 | 56億2911万 | +6.67% |
| 10/28 | 362 | 363 | 356 | 361 | +0.84% | 69,800 | 55億2203万 | +5.25% |
| 10/25 | 349 | 358 | 349 | 358 | +2.29% | 63,000 | 54億7614万 | +4.99% |
| 10/24 | 354 | 356 | 349 | 350 | -1.41% | 43,900 | 53億5377万 | +3.24% |
| 10/23 | 363 | 363 | 353 | 355 | -0.56% | 60,200 | 54億3025万 | +5.03% |
| 10/21 | 340 | 360 | 340 | 357 | +4.08% | 91,600 | 54億6085万 | +5.93% |
| 10/18 | 341 | 347 | 341 | 343 | +2.39% | 99,900 | 52億4669万 | +2.39% |
| 10/17 | 344 | 348 | 335 | 335 | -2.9% | 106,700 | 51億2432万 | +0.3% |
| 10/16 | 339 | 350 | 339 | 345 | +4.23% | 235,700 | 52億7729万 | +3.6% |
| 10/15 | （IR情報）15:00 国立大学法人東京大学との感染症予防ワクチンに関する共同研究開始のお知らせ |
| 10/15 | 326 | 335 | 325 | 331 | +1.22% | 102,400 | 50億6314万 | -0.3% |
| 10/15 | （空売り報告）Credit Suisse Securities (Europe) Limited 81,545株（0.46%）-0.07%義務消失 |
| 10/11 | 339 | 344 | 325 | 327 | -5.22% | 287,600 | 50億195万 | -1.51% |
| 10/11 | （空売り報告）Credit Suisse Securities (Europe) Limited 94,045株（0.53%）再IN |
| 10/10 | 362 | 364 | 341 | 345 | -4.96% | 242,900 | 52億7729万 | +4.23% |
| 10/09 | 366 | 369 | 353 | 363 | -0.27% | 162,100 | 55億5262万 | +10% |
| 10/08 | 356 | 371 | 351 | 364 | +1.39% | 162,900 | 55億6792万 | +10.98% |
| 10/07 | 379 | 379 | 358 | 359 | -2.45% | 247,200 | 54億9144万 | +10.12% |
| 10/04 | 362 | 379 | 352 | 368 | +6.36% | 605,100 | 56億2911万 | +13.58% |
| 10/03 | （IR情報）17:15 第1回無担保転換社債型新株予約権付社債の行使請求受領に関するお知らせ |
| 10/03 | 340 | 353 | 332 | 346 | +0.87% | 211,000 | 52億9258万 | +7.45% |
| 10/02 | 360 | 372 | 341 | 343 | -0.29% | 859,500 | 52億4669万 | +7.19% |
| 10/01 | （IR情報）15:00 塩野義製薬株式会社との資本業務提携に係る第4回開発マイルストーン達成確認に関するお知らせ |
| 10/01 | 347 | 350 | 335 | 344 | 0% | 173,800 | 52億6199万 | +8.18% |
| 09/30 | 326 | 353 | 326 | 344 | +6.5% | 410,000 | 52億6199万 | +8.52% |
| 09/27 | 330 | 332 | 323 | 323 | +0.94% | 71,500 | 49億4076万 | +2.54% |
