| 2018 |
| 06/04 | 1,579 | 1,579 | 1,551 | 1,561 | -0.51% | 83,700 | 886億8679万 | -7.36% |
| 06/01 | 1,541 | 1,583 | 1,541 | 1,569 | +1.69% | 137,700 | 891億4131万 | -7.49% |
| 05/31 | 1,540 | 1,546 | 1,528 | 1,543 | +0.59% | 125,900 | 876億6414万 | -9.55% |
| 05/30 | 1,540 | 1,548 | 1,530 | 1,534 | -1.22% | 132,500 | 871億5281万 | -10.71% |
| 05/29 | 1,575 | 1,580 | 1,551 | 1,553 | -1.4% | 93,800 | 882億3228万 | -10.28% |
| 05/28 | 1,600 | 1,602 | 1,571 | 1,575 | -1.56% | 106,900 | 894億8219万 | -9.69% |
| 05/25 | 1,607 | 1,620 | 1,598 | 1,600 | -0.44% | 102,900 | 909億254万 | -8.88% |
| 05/24 | 1,629 | 1,644 | 1,603 | 1,607 | -1.35% | 150,900 | 913億24万 | -9.05% |
| 05/23 | 1,618 | 1,636 | 1,612 | 1,629 | +0.49% | 114,600 | 925億5015万 | -8.38% |
| 05/22 | （IR情報）10:00 腰椎椎間板ヘルニア治療剤「ヘルニコア椎間板注用1.25単位」の国内における薬価基準収載及び発売時期に関するお知らせ |
| 05/22 | 1,630 | 1,630 | 1,604 | 1,621 | -0.86% | 189,900 | 920億9564万 | -9.34% |
| 05/21 | （IR情報）10:00 癒着防止材SI-449の臨床試験開始に関するお知らせ |
| 05/21 | 1,635 | 1,654 | 1,628 | 1,635 | +0.25% | 138,800 | 928億9104万 | -9.17% |
| 05/18 | 1,635 | 1,641 | 1,611 | 1,631 | -0.67% | 125,400 | 926億6378万 | -9.94% |
| 05/17 | 1,615 | 1,650 | 1,602 | 1,642 | +1.8% | 203,500 | 932億8874万 | -10.03% |
| 05/16 | 1,769 | 1,769 | 1,594 | 1,613 | -9.02% | 533,700 | 916億4113万 | -12.34% |
| 05/15 | 1,745 | 1,787 | 1,744 | 1,773 | +2.13% | 139,500 | 1007億3138万 | -4.37% |
| 05/14 | 1,627 | 1,769 | 1,627 | 1,736 | -3.5% | 277,000 | 986億2926万 | -6.67% |
| 05/11 | （IR情報）16:00 2018年3月期決算短信〔日本基準〕(連結) |
| 05/11 | 1,772 | 1,800 | 1,754 | 1,799 | +0.67% | 138,100 | 1022億855万 | -3.69% |
| 05/10 | 1,800 | 1,806 | 1,781 | 1,787 | -0.94% | 69,200 | 1015億2678万 | -4.59% |
| 05/09 | 1,850 | 1,850 | 1,793 | 1,804 | -2.49% | 147,100 | 1024億9262万 | -4.04% |
| 05/08 | 1,835 | 1,865 | 1,835 | 1,850 | +0.82% | 96,200 | 1051億607万 | -1.86% |
| 05/07 | 1,793 | 1,843 | 1,782 | 1,835 | +2.17% | 111,900 | 1042億5386万 | -2.86% |
| 05/02 | 1,780 | 1,805 | 1,780 | 1,796 | +0.45% | 73,700 | 1020億3811万 | -5.17% |
| 05/01 | 1,817 | 1,823 | 1,785 | 1,788 | -1.6% | 97,800 | 1015億8359万 | -5.89% |
| 04/27 | 1,835 | 1,862 | 1,803 | 1,817 | -0.76% | 131,900 | 1032億3120万 | -4.57% |
| 04/26 | 1,830 | 1,836 | 1,806 | 1,831 | +0.27% | 107,200 | 1040億2660万 | -4.04% |
| 04/25 | 1,819 | 1,845 | 1,818 | 1,826 | -0.16% | 82,400 | 1037億4253万 | -4.6% |
| 04/24 | （IR情報）15:00 組織変更並びに代表取締役及び役員等の異動に関するお知らせ |
| 04/24 | 1,844 | 1,844 | 1,822 | 1,829 | -0.11% | 97,600 | 1039億1297万 | -4.64% |
| 04/23 | 1,859 | 1,859 | 1,827 | 1,831 | -1.51% | 80,700 | 1040億2660万 | -4.78% |
| 04/20 | 1,860 | 1,870 | 1,850 | 1,859 | -0.91% | 90,900 | 1056億1739万 | -3.63% |
| 04/19 | 1,879 | 1,882 | 1,853 | 1,876 | -0.27% | 84,500 | 1065億8323万 | -3% |
| 04/18 | 1,889 | 1,905 | 1,872 | 1,881 | +0.64% | 74,600 | 1068億6730万 | -2.94% |
| 04/17 | 1,880 | 1,891 | 1,862 | 1,869 | -1.74% | 74,700 | 1061億8553万 | -3.86% |
| 04/16 | （5%ルール）エム・ユー投資顧問（0%）三菱UFJ銀行（2.7%）三菱UFJ信託銀行（2.24%）三菱UFJ国際投信（0.46%） |
| 04/16 | 1,887 | 1,905 | 1,864 | 1,902 | +1.82% | 102,900 | 1080億6040万 | -2.41% |
| 04/13 | 1,921 | 1,921 | 1,858 | 1,868 | -2.45% | 191,700 | 1061億2872万 | -4.25% |
| 04/12 | 1,915 | 1,938 | 1,906 | 1,915 | 0% | 48,900 | 1087億9898万 | -2.1% |
| 04/11 | 1,981 | 1,981 | 1,912 | 1,915 | -3.62% | 92,600 | 1087億9898万 | -2.3% |
| 04/10 | 2,015 | 2,025 | 1,980 | 1,987 | -1.24% | 164,000 | 1128億8960万 | +1.17% |
| 04/09 | 1,961 | 2,018 | 1,952 | 2,012 | +2.44% | 152,300 | 1143億995万 | +2.34% |
| 04/06 | 1,931 | 1,973 | 1,925 | 1,964 | +2.13% | 142,200 | 1115億8287万 | -0.2% |
| 04/05 | 1,949 | 1,949 | 1,904 | 1,923 | -0.16% | 143,300 | 1092億5350万 | -2.48% |
| 04/04 | 1,946 | 1,955 | 1,923 | 1,926 | -0.1% | 84,400 | 1094億2394万 | -2.73% |
| 04/03 | 1,920 | 1,934 | 1,889 | 1,928 | -1.78% | 192,100 | 1095億3757万 | -2.97% |
| 04/02 | 1,980 | 1,997 | 1,959 | 1,963 | +1.19% | 280,000 | 1115億2606万 | -1.55% |
| 03/30 | （IR情報）15:00 2018年3月期通期連結業績予想の修正に関するお知らせ |
| 03/30 | （IR情報）15:00 役員等の異動に関するお知らせ |
| 03/30 | 1,947 | 1,947 | 1,912 | 1,940 | +0.26% | 108,900 | 1102億1934万 | -3.1% |
| 03/29 | 1,972 | 1,972 | 1,917 | 1,935 | -1.23% | 105,800 | 1099億3526万 | -3.83% |
| 03/28 | 1,938 | 1,960 | 1,922 | 1,959 | +0.41% | 86,200 | 1112億9880万 | -3.02% |
| 03/27 | 1,920 | 1,958 | 1,920 | 1,951 | +2.41% | 132,400 | 1108億4429万 | -3.65% |
| 03/26 | 1,897 | 1,935 | 1,874 | 1,905 | +0.37% | 171,000 | 1082億3084万 | -6.25% |
| 03/23 | （IR情報）15:00 腰椎椎間板ヘルニア治療剤「ヘルニコア椎間板注用1.25単位」の国内における製造販売承認取得に関するお知らせ |
| 03/23 | 1,930 | 1,938 | 1,894 | 1,898 | -4.58% | 173,600 | 1078億3314万 | -6.92% |
| 03/22 | 1,920 | 1,994 | 1,916 | 1,989 | +2.68% | 136,000 | 1130億323万 | -2.12% |
| 03/20 | 1,934 | 1,946 | 1,916 | 1,937 | -0.87% | 107,700 | 1100億4889万 | -4.16% |
| 03/19 | 1,972 | 1,974 | 1,909 | 1,954 | -0.91% | 190,200 | 1110億1473万 | -2.93% |
| 03/16 | 1,969 | 1,989 | 1,967 | 1,972 | -0.25% | 123,300 | 1120億3739万 | -1.6% |
| 03/15 | 1,986 | 1,999 | 1,953 | 1,977 | -0.7% | 126,500 | 1123億2146万 | -0.85% |
| 03/14 | 2,017 | 2,027 | 1,982 | 1,991 | -1.78% | 115,000 | 1131億1685万 | +0.45% |
| 03/13 | 1,985 | 2,035 | 1,977 | 2,027 | +2.63% | 130,100 | 1151億6216万 | +3.05% |
| 03/12 | 1,999 | 2,009 | 1,959 | 1,975 | +0.15% | 122,300 | 1122億783万 | +0.92% |
| 03/09 | 2,022 | 2,038 | 1,964 | 1,972 | -1.1% | 161,900 | 1120億3739万 | +1.23% |
| 03/08 | 2,006 | 2,011 | 1,982 | 1,994 | -0.85% | 119,600 | 1132億8730万 | +2.84% |
| 03/07 | 1,987 | 2,028 | 1,964 | 2,011 | -0.45% | 212,100 | 1142億5314万 | +4.36% |
| 03/06 | 2,037 | 2,046 | 1,988 | 2,020 | -0.05% | 197,000 | 1147億6446万 | +5.48% |
| 03/05 | 2,059 | 2,070 | 2,005 | 2,021 | -2.27% | 196,000 | 1148億2128万 | +6.14% |
| 03/02 | 2,074 | 2,124 | 2,050 | 2,068 | 0% | 293,900 | 1174億9154万 | +9.3% |
| 03/01 | 2,092 | 2,105 | 2,059 | 2,068 | -1.9% | 149,500 | 1174億9154万 | +10.12% |
| 02/28 | 2,095 | 2,142 | 2,095 | 2,108 | -0.19% | 211,200 | 1197億6410万 | +12.97% |
| 02/27 | 2,113 | 2,160 | 2,104 | 2,112 | +0.91% | 258,500 | 1199億9136万 | +14.1% |
| 02/26 | 2,203 | 2,205 | 2,091 | 2,093 | -4.17% | 346,000 | 1189億1189万 | +13.94% |
| 02/23 | 2,200 | 2,236 | 2,177 | 2,184 | +0.65% | 481,800 | 1240億8197万 | +19.87% |
| 02/22 | 2,150 | 2,184 | 2,142 | 2,170 | +1.59% | 313,900 | 1232億8658万 | +20.35% |
| 02/21 | 2,090 | 2,164 | 2,070 | 2,136 | +1.62% | 406,500 | 1213億5490万 | +19.73% |
| 02/20 | 2,100 | 2,135 | 2,079 | 2,102 | -0.43% | 313,300 | 1194億2322万 | +18.89% |
| 02/19 | （IR情報）10:00 腰椎椎間板ヘルニア治療剤SI-6603の米国における第III相臨床試験(追加試験)開始に関するお知らせ |
| 02/19 | 2,067 | 2,130 | 2,043 | 2,111 | +1.69% | 675,300 | 1199億3455万 | +20.42% |
| 02/16 | 2,055 | 2,090 | 1,949 | 2,076 | +20.35% | 1,496,200 | 1179億4605万 | +19.52% |
| 02/15 | 1,711 | 1,735 | 1,695 | 1,725 | +0.82% | 158,400 | 980億431万 | +0.12% |
| 02/14 | 1,736 | 1,753 | 1,694 | 1,711 | -1.55% | 110,100 | 972億891万 | -0.7% |
| 02/13 | 1,750 | 1,767 | 1,718 | 1,738 | +0.4% | 233,200 | 987億4289万 | +0.93% |
| 02/09 | 1,670 | 1,732 | 1,658 | 1,731 | -0.17% | 230,300 | 983億4519万 | +0.64% |
| 02/08 | 1,701 | 1,759 | 1,701 | 1,734 | +4.08% | 237,500 | 985億1563万 | +0.87% |
| 02/07 | 1,699 | 1,736 | 1,665 | 1,666 | +2.46% | 200,400 | 946億5227万 | -2.97% |
| 02/06 | 1,682 | 1,690 | 1,592 | 1,626 | -8.91% | 417,700 | 923億7971万 | -5.3% |
| 02/05 | 1,769 | 1,860 | 1,768 | 1,785 | +2.65% | 715,600 | 1014億1315万 | +3.84% |
| 02/02 | （IR情報）15:00 組織変更および役員等の異動に関するお知らせ |
| 02/02 | （IR情報）15:00 2018年3月期第3四半期決算短信〔日本基準〕(連結) |
| 02/02 | 1,748 | 1,756 | 1,728 | 1,739 | 0% | 143,500 | 987億9970万 | +1.4% |
| 02/01 | 1,707 | 1,742 | 1,705 | 1,739 | +1.64% | 88,100 | 987億9970万 | +1.52% |
| 01/31 | 1,708 | 1,735 | 1,700 | 1,711 | -0.12% | 114,900 | 972億891万 | 0% |
| 01/30 | 1,730 | 1,741 | 1,712 | 1,713 | -1.21% | 106,900 | 973億2254万 | +0.18% |
| 01/29 | 1,738 | 1,758 | 1,731 | 1,734 | +0.23% | 93,000 | 985億1563万 | +1.58% |
| 01/26 | 1,715 | 1,746 | 1,712 | 1,730 | +0.99% | 88,400 | 982億8838万 | +1.53% |
| 01/25 | 1,736 | 1,743 | 1,711 | 1,713 | -2.28% | 143,000 | 973億2254万 | +0.71% |
| 01/24 | 1,756 | 1,758 | 1,739 | 1,753 | -0.11% | 88,000 | 995億9510万 | +3.24% |
| 01/23 | 1,739 | 1,765 | 1,734 | 1,755 | +0.98% | 114,400 | 997億873万 | +3.48% |
| 01/22 | 1,725 | 1,759 | 1,722 | 1,738 | +0.75% | 344,100 | 987億4289万 | +2.6% |
| 01/19 | 1,712 | 1,729 | 1,711 | 1,725 | +0.76% | 97,100 | 980億431万 | +1.95% |
| 01/18 | 1,715 | 1,736 | 1,707 | 1,712 | +0.65% | 197,800 | 972億6572万 | +1.24% |
| 01/17 | 1,726 | 1,729 | 1,696 | 1,701 | -1.1% | 121,600 | 966億4077万 | +0.71% |
| 01/16 | 1,726 | 1,740 | 1,712 | 1,720 | -0.46% | 117,500 | 977億2023万 | +2.02% |
| 01/15 | 1,720 | 1,738 | 1,718 | 1,728 | +0.47% | 100,700 | 981億7475万 | +2.73% |
| 01/12 | （IR情報）17:00 執行役員の役職異動に関するお知らせ |
| 01/12 | 1,735 | 1,735 | 1,718 | 1,720 | -1.15% | 105,300 | 977億2023万 | +2.5% |
| 01/11 | 1,700 | 1,744 | 1,700 | 1,740 | +1.99% | 212,600 | 988億5652万 | +3.94% |
| 01/10 | 1,695 | 1,711 | 1,682 | 1,706 | +0.59% | 137,400 | 969億2484万 | +2.09% |
| 01/09 | 1,700 | 1,706 | 1,690 | 1,696 | -0.06% | 114,900 | 963億5670万 | +1.74% |
