| 2022 |
| 01/07 | 3,741 | 3,766 | 3,672 | 3,725 | -0.24% | 2,622,100 | 6兆2544億 | -0.13% |
| 01/06 | 3,797 | 3,824 | 3,734 | 3,734 | -1.61% | 2,164,600 | 6兆2696億 | +0.19% |
| 01/05 | 3,834 | 3,842 | 3,786 | 3,795 | -0.86% | 2,069,700 | 6兆3720億 | +1.88% |
| 01/04 | 3,770 | 3,839 | 3,714 | 3,828 | +2.49% | 1,959,600 | 6兆4274億 | +2.77% |
| 2021 |
| 12/30 | 3,765 | 3,789 | 3,735 | 3,735 | -0.98% | 1,555,700 | 6兆2712億 | +0.16% |
| 12/29 | 3,764 | 3,801 | 3,742 | 3,772 | -0.66% | 1,185,700 | 6兆3334億 | +0.8% |
| 12/28 | 3,737 | 3,808 | 3,736 | 3,797 | +1.33% | 1,583,200 | 6兆3753億 | +1.15% |
| 12/27 | 3,740 | 3,772 | 3,728 | 3,747 | -0.58% | 1,339,300 | 6兆2914億 | -0.58% |
| 12/24 | 3,750 | 3,775 | 3,738 | 3,769 | +0.51% | 1,094,400 | 6兆3283億 | -0.37% |
| 12/23 | 3,728 | 3,750 | 3,705 | 3,750 | +0.21% | 1,148,900 | 6兆2964億 | -1.26% |
| 12/22 | 3,703 | 3,748 | 3,702 | 3,742 | +1.14% | 1,759,400 | 6兆2830億 | -1.89% |
| 12/21 | 3,679 | 3,712 | 3,650 | 3,700 | +2.29% | 2,216,500 | 6兆2125億 | -3.42% |
| 12/20 | 3,612 | 3,676 | 3,591 | 3,617 | +0.14% | 2,576,500 | 6兆731億 | -6.08% |
| 12/17 | （IR情報）17:00 新市場区分「プライム市場」の選択申請に関する取締役会決議のお知らせ |
| 12/17 | 3,694 | 3,720 | 3,612 | 3,612 | -5.2% | 4,377,800 | 6兆647億 | -6.69% |
| 12/16 | 3,836 | 3,836 | 3,777 | 3,810 | +1.76% | 2,728,600 | 6兆3972億 | -2.08% |
| 12/15 | 3,770 | 3,777 | 3,727 | 3,744 | -0.87% | 2,278,700 | 6兆2863億 | -4.05% |
| 12/14 | 3,838 | 3,838 | 3,744 | 3,777 | +0.8% | 2,706,500 | 6兆3418億 | -3.48% |
| 12/13 | 3,788 | 3,796 | 3,731 | 3,747 | +1.27% | 1,662,200 | 6兆2914億 | -4.56% |
| 12/10 | 3,761 | 3,771 | 3,693 | 3,700 | -2.37% | 3,209,400 | 6兆2125億 | -6.23% |
| 12/09 | 3,838 | 3,848 | 3,787 | 3,790 | -2.17% | 2,349,500 | 6兆3636億 | -4.53% |
| 12/08 | 3,788 | 3,904 | 3,769 | 3,874 | +6.78% | 3,830,100 | 6兆5046億 | -2.93% |
| 12/07 | 3,598 | 3,658 | 3,539 | 3,628 | +2.83% | 3,146,500 | 6兆916億 | -9.48% |
| 12/06 | 3,625 | 3,645 | 3,490 | 3,528 | -4.03% | 2,851,700 | 5兆9237億 | -12.52% |
| 12/03 | 3,662 | 3,697 | 3,630 | 3,676 | +0.3% | 2,313,000 | 6兆1722億 | -9.5% |
| 12/02 | 3,646 | 3,688 | 3,630 | 3,665 | +0.85% | 2,596,100 | 6兆1537億 | -10.33% |
| 12/01 | 3,663 | 3,699 | 3,610 | 3,634 | -1.25% | 2,551,900 | 6兆1016億 | -11.58% |
| 11/30 | 3,833 | 3,851 | 3,666 | 3,680 | -3.16% | 5,112,600 | 6兆1789億 | -11% |
| 11/29 | 3,900 | 3,922 | 3,784 | 3,800 | -3.18% | 3,060,500 | 6兆3804億 | -8.23% |
| 11/26 | 4,020 | 4,043 | 3,906 | 3,925 | -3.28% | 2,635,700 | 6兆5903億 | -5.28% |
| 11/25 | 4,051 | 4,107 | 4,044 | 4,058 | -0.49% | 1,255,900 | 6兆8136億 | -2.12% |
| 11/24 | 4,133 | 4,155 | 4,063 | 4,078 | -2.16% | 1,506,200 | 6兆8471億 | -1.57% |
| 11/22 | 4,098 | 4,183 | 4,081 | 4,168 | +1.36% | 1,384,900 | 6兆9983億 | +0.75% |
| 11/19 | 4,133 | 4,143 | 4,073 | 4,112 | -0.51% | 1,455,400 | 6兆9042億 | -0.44% |
| 11/18 | 4,121 | 4,188 | 4,104 | 4,133 | -0.43% | 1,303,400 | 6兆9395億 | +0.24% |
| 11/17 | 4,148 | 4,159 | 4,103 | 4,151 | -0.34% | 1,376,500 | 6兆9697億 | +0.9% |
| 11/16 | 4,155 | 4,220 | 4,150 | 4,165 | -0.93% | 1,211,700 | 6兆9932億 | +1.46% |
| 11/15 | 4,115 | 4,217 | 4,114 | 4,204 | +2.09% | 1,556,800 | 7兆587億 | +2.66% |
| 11/12 | （IR情報）11:30 新型コロナウイルス感染症の外来患者を対象としたAT-527の臨床試験に関するアテア社発表について |
| 11/12 | 4,150 | 4,159 | 4,102 | 4,118 | +0.15% | 2,200,600 | 6兆9143億 | +0.86% |
| 11/11 | 4,060 | 4,133 | 4,058 | 4,112 | +0.88% | 1,644,900 | 6兆9042億 | +0.96% |
| 11/10 | 4,020 | 4,097 | 4,014 | 4,076 | +1.37% | 1,352,000 | 6兆8438億 | +0.3% |
| 11/09 | 4,095 | 4,110 | 4,012 | 4,021 | -1.93% | 1,879,800 | 6兆7514億 | -1.01% |
| 11/08 | 4,249 | 4,250 | 4,082 | 4,100 | -3.71% | 2,566,400 | 6兆8841億 | +0.81% |
| 11/05 | 4,376 | 4,376 | 4,242 | 4,258 | -1.11% | 2,121,300 | 7兆1494億 | +4.7% |
| 11/04 | 4,390 | 4,399 | 4,303 | 4,306 | +0.05% | 3,194,600 | 7兆2300億 | +6.03% |
| 11/02 | 4,298 | 4,305 | 4,282 | 4,304 | -0.05% | 1,933,000 | 7兆2266億 | +6.19% |
| 11/01 | 4,297 | 4,306 | 4,269 | 4,306 | +1.39% | 2,885,300 | 7兆2300億 | +6.35% |
| 10/29 | 4,247 | 4,287 | 4,214 | 4,247 | +0.02% | 2,958,000 | 7兆1309億 | +4.97% |
| 10/28 | 4,270 | 4,301 | 4,235 | 4,246 | -1.26% | 2,593,600 | 7兆1292億 | +4.89% |
| 10/27 | 4,273 | 4,313 | 4,250 | 4,300 | +1.15% | 3,459,500 | 7兆2199億 | +6.33% |
| 10/26 | 4,239 | 4,266 | 4,165 | 4,251 | +0.12% | 4,521,300 | 7兆1376億 | +5.3% |
| 10/25 | 3,981 | 4,259 | 3,971 | 4,246 | +10.54% | 9,517,700 | 7兆1292億 | +5.23% |
| 10/22 | （IR情報）17:00 2021年12月期配当予想の修正に関するお知らせ |
| 10/22 | （IR情報）17:00 業績予想の修正に関するお知らせ |
| 10/22 | （IR情報）17:00 2021年12月期第3四半期連結決算〔IFRS〕補足資料 |
| 10/22 | （IR情報）17:00 2021年12月期第3四半期決算短信〔IFRS〕(連結) |
| 10/22 | 3,831 | 3,869 | 3,827 | 3,841 | -0.93% | 2,341,500 | 6兆4492億 | -4.69% |
| 10/21 | 3,935 | 3,969 | 3,877 | 3,877 | -2.29% | 2,078,600 | 6兆5097億 | -4.11% |
| 10/20 | （IR情報）14:00 エフ・ホフマン・ラ・ロシュの2021年第3四半期の販売実績について |
| 10/20 | 3,984 | 3,997 | 3,947 | 3,968 | -0.4% | 2,043,100 | 6兆6625億 | -2.17% |
| 10/19 | （IR情報）17:00 がんのウイルス療法「OBP-301(テロメライシン)」に関する独占的ライセンス契約解消の決定に関するお知らせ |
| 10/19 | 3,927 | 3,991 | 3,927 | 3,984 | +1.58% | 1,687,800 | 6兆6893億 | -2.04% |
| 10/18 | 3,997 | 3,997 | 3,916 | 3,922 | -1.7% | 1,699,800 | 6兆5852億 | -3.75% |
| 10/15 | 3,970 | 3,994 | 3,935 | 3,990 | +0.76% | 1,847,500 | 6兆6994億 | -2.37% |
| 10/14 | 3,929 | 3,970 | 3,895 | 3,960 | +1.36% | 1,845,200 | 6兆6490億 | -3.44% |
| 10/13 | 3,882 | 3,930 | 3,866 | 3,907 | -0.23% | 1,346,400 | 6兆5600億 | -5.15% |
| 10/12 | 3,968 | 3,969 | 3,896 | 3,916 | -0.2% | 2,076,400 | 6兆5751億 | -5.41% |
| 10/11 | 3,887 | 3,941 | 3,854 | 3,924 | +0.93% | 3,037,600 | 6兆5886億 | -5.67% |
| 10/08 | 3,934 | 3,969 | 3,882 | 3,888 | +0.26% | 3,258,000 | 6兆5281億 | -6.9% |
| 10/07 | 3,909 | 3,925 | 3,868 | 3,878 | -0.44% | 2,827,100 | 6兆5113億 | -7.56% |
| 10/06 | 4,013 | 4,018 | 3,875 | 3,895 | -3.23% | 4,262,000 | 6兆5399億 | -7.53% |
| 10/05 | 4,072 | 4,105 | 4,010 | 4,025 | -2.82% | 2,532,100 | 6兆7582億 | -4.76% |
| 10/04 | 4,176 | 4,206 | 4,131 | 4,142 | +0.88% | 2,594,900 | 6兆9546億 | -2.24% |
| 10/01 | 4,114 | 4,148 | 4,088 | 4,106 | +0.07% | 2,847,200 | 6兆8942億 | -3.21% |
| 09/30 | 4,123 | 4,149 | 4,083 | 4,103 | -0.1% | 3,730,100 | 6兆8891億 | -3.46% |
| 09/29 | 4,130 | 4,157 | 4,081 | 4,107 | -2.05% | 3,323,300 | 6兆8958億 | -3.5% |
| 09/28 | 4,203 | 4,210 | 4,133 | 4,193 | -0.83% | 2,955,600 | 7兆402億 | -1.67% |
| 09/27 | 4,300 | 4,309 | 4,207 | 4,228 | -1.77% | 2,376,500 | 7兆990億 | -0.94% |
| 09/24 | 4,220 | 4,307 | 4,183 | 4,304 | +4.09% | 4,162,900 | 7兆2266億 | +0.77% |
| 09/22 | 4,142 | 4,167 | 4,096 | 4,135 | +0.15% | 1,904,100 | 6兆9429億 | -3% |
| 09/21 | 4,186 | 4,194 | 4,118 | 4,129 | -1.62% | 2,091,700 | 6兆9328億 | -3.08% |
| 09/17 | 4,149 | 4,199 | 4,135 | 4,197 | +1.7% | 3,097,300 | 7兆470億 | -1.39% |
| 09/16 | 4,168 | 4,193 | 4,090 | 4,127 | -0.98% | 2,580,000 | 6兆9294億 | -2.94% |
| 09/15 | 4,180 | 4,222 | 4,163 | 4,168 | -0.71% | 1,689,900 | 6兆9983億 | -1.95% |
| 09/14 | 4,256 | 4,272 | 4,186 | 4,198 | -1.18% | 2,904,500 | 7兆486億 | -1.18% |
| 09/13 | 4,165 | 4,251 | 4,157 | 4,248 | +1.75% | 2,167,800 | 7兆1326億 | +0.12% |
| 09/10 | 4,179 | 4,191 | 4,156 | 4,175 | -1.44% | 4,836,300 | 7兆100億 | -1.37% |
| 09/09 | 4,295 | 4,297 | 4,231 | 4,236 | -2.1% | 3,028,000 | 7兆1124億 | +0.24% |
| 09/08 | 4,360 | 4,380 | 4,327 | 4,327 | -1.86% | 3,462,700 | 7兆2652億 | +2.63% |
| 09/07 | 4,471 | 4,480 | 4,403 | 4,409 | -0.85% | 2,410,500 | 7兆4029億 | +4.9% |
| 09/06 | 4,464 | 4,490 | 4,431 | 4,447 | +0.79% | 2,804,600 | 7兆4667億 | +6.11% |
| 09/03 | 4,340 | 4,417 | 4,322 | 4,412 | +2.13% | 3,415,300 | 7兆4080億 | +5.7% |
| 09/02 | 4,372 | 4,379 | 4,302 | 4,320 | -1.19% | 2,663,500 | 7兆2535億 | +3.82% |
| 09/01 | 4,330 | 4,388 | 4,302 | 4,372 | +1.49% | 3,378,200 | 7兆3408億 | +5.3% |
| 08/31 | 4,254 | 4,318 | 4,245 | 4,308 | +1.56% | 3,152,500 | 7兆2333億 | +3.96% |
| 08/30 | 4,287 | 4,292 | 4,204 | 4,242 | -0.98% | 1,997,900 | 7兆1225億 | +2.49% |
| 08/27 | 4,284 | 4,300 | 4,252 | 4,284 | -0.02% | 1,938,300 | 7兆1930億 | +3.63% |
| 08/26 | 4,300 | 4,311 | 4,276 | 4,285 | -0.21% | 2,577,100 | 7兆1947億 | +3.78% |
| 08/25 | 4,282 | 4,312 | 4,241 | 4,294 | +0.75% | 3,308,400 | 7兆2098億 | +4.15% |
| 08/24 | 4,275 | 4,305 | 4,246 | 4,262 | -0.88% | 2,074,300 | 7兆1561億 | +3.6% |
| 08/23 | 4,330 | 4,340 | 4,286 | 4,300 | +0.37% | 2,705,800 | 7兆2199億 | +4.65% |
| 08/20 | 4,330 | 4,343 | 4,272 | 4,284 | -0.4% | 4,065,100 | 7兆1930億 | +4.36% |
| 08/19 | 4,122 | 4,327 | 4,120 | 4,301 | +4.52% | 6,679,900 | 7兆2216億 | +4.8% |
| 08/18 | 4,110 | 4,179 | 4,092 | 4,115 | +1.13% | 3,180,000 | 6兆9093億 | +0.32% |
| 08/17 | 4,046 | 4,097 | 4,039 | 4,069 | +1.32% | 2,201,300 | 6兆8320億 | -0.8% |
| 08/16 | 4,092 | 4,100 | 4,003 | 4,016 | -2.24% | 2,178,800 | 6兆7430億 | -2.24% |
| 08/13 | 4,108 | 4,124 | 4,087 | 4,108 | +0.34% | 2,667,500 | 6兆8975億 | -0.19% |
